Fig. 5 | Communications Biology

Fig. 5

From: Wnt5a is a TLR2/4-ligand that induces tolerance in human myeloid cells

Fig. 5

Suggested protein–protein binding model for WntD/Toll. a The protein–protein binding between Drosophila Toll (a TLR4 homologue) and WntD (Wnt5a homologue) was modelled using Rosetta macromolecular modelling package49. Energy landscapes from the docking perturbation simulations. In this plot the energy of models is plotted against root mean square deviation (rmsd) against the lowest energy model (interface rmsd). b A proposed protein–protein docking model of how WntD may interact with Toll

Back to article page