Fig. 4 | Communications Biology

Fig. 4

From: SLO potassium channels antagonize premature decision making in C. elegans

Fig. 4

SLO K+ channels act in the AFD thermosensory neuron to decelerate preference transition in thermotaxis. a Animals expressing the H159Y mutant form of SLO-2 isoform b under the control of promoters indicated were cultivated at 17 °C for 5 days and then at 23 °C for 3 h and subjected to thermotaxis assay. The fractions of animals and thermotaxis indices are plotted. n = 17, 17, 4, 5, 4, 4, 4. ***p < 0.001 (Dunnett test against wild type). b Wild-type animals, wild-type animals that express SLO-1 in AFD after insertion of a single copy of a transgene into a genome, slo-1(eg142); slo-2(nf101) animals, and slo-1(eg142); slo-2(nf101) animals that express SLO-1 in AFD after insertion of a single copy of a transgene were cultivated at 17 °C for 5 days and then at 23 °C for 1 h. Animals were then subjected to thermotaxis assay. n = 4. p Values are indicated (Tukey-Kramer test). c Wild-type animals, wild-type animals that express SLO-2 in AFD after insertion of a single copy of a transgene into a genome, slo-1(eg142); slo-2(nf101) animals, and slo-1(eg142); slo-2(nf101) animals that express SLO-2 in AFD after insertion of a single copy of a transgene were cultivated at 17 °C for 5 days and then at 23 °C for 45 min. Animals were then subjected to thermotaxis assay. n = 8. p Values are indicated (Tukey-Kramer test). See also Supplementary Fig. 4

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