Fig. 3 | Communications Biology

Fig. 3

From: Sea turtle fibropapilloma tumors share genomic drivers and therapeutic vulnerabilities with human cancers

Fig. 3

Transcripts differentially expressed in fibropapillomatosis are associated with nervous system development. a Protein–protein interaction map of the top differentially expressed transcripts (RNA-seq) with homology to characterized human genes. Generated from the top 600 (300 per direction of regulation) differentially expressed transcripts. Nervous system development-related nodes are highlighted by red shading. Network generated by the STRING database54 (v10.5, http://www.stringdb.org), with the inbuilt KEGG pathway enrichment analysis tool applied to this network. b Fold change in expression of the differentially expressed transcripts (RNA-seq) related to nervous system development (KEGG), listed in order of false discovery rate (FDR, KEGG pathway enrichment analysis tool). Transcript expression values underlying the differential expression analysis are provided in Supplementary Table 4