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Biohybrid catalysis

Pushing hybrids to the limits

Photosynthetic semiconductor biohybrids represent a viable approach to solar-to-chemical production but it remains challenging to tap their full potential. Now, a microbe–quantum dot hybrid has been developed for simultaneous fixation of CO2 and N2 with internal quantum efficiencies approaching the theoretical limits.

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Fig. 1: Maximizing light-driven CO2 and N2 fixation in biological–material hybrids.


  1. Cestellos-Blanco, S., Zhang, H., Kim, J. M., Shen, Y.-X. & Yang, P. Nat. Catal. 3, 245–255 (2020).

    Article  CAS  Google Scholar 

  2. Sakimoto, K. K., Wong, A. B. & Yang, P. Science 351, 74–77 (2016).

    Article  CAS  PubMed  Google Scholar 

  3. Zhang, H. et al. Nat. Nanotechnol. 13, 900–905 (2018).

    Article  CAS  PubMed  Google Scholar 

  4. Bertram, J. R., Ding, Y. & Nagpal, P. Nanoscale Adv. 2, 2363–2370 (2020).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Ding, Y. et al. J. Am. Chem. Soc. 141, 10272–10282 (2019).

    Article  CAS  PubMed  Google Scholar 

  6. Guan, X. et al. Nat. Catal. (2022).

    Article  Google Scholar 

  7. Xiao, K. et al. Energy Environ. Sci. 15, 529–549 (2022).

    Article  CAS  Google Scholar 

  8. Fang, X., Kalathil, S. & Reisner, E. Chem. Soc. Rev. 49, 4926–4952 (2020).

    Article  CAS  PubMed  Google Scholar 

  9. Nielsen, J. & Keasling, J. D. Cell 164, 1185–1197 (2016).

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Xiulai Chen.

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The authors declare no competing interests.

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Zhang, J., Liu, L. & Chen, X. Pushing hybrids to the limits. Nat Catal 5, 975–976 (2022).

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