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Metabolic Engineering

Modular biocatalysis for polyamines

Polyamines are a growing class of medically and agriculturally active biomolecules that have traditionally been difficult to source. Now, a bio-based platform for high-level production of diverse polyamines has been realized, showing the versatility of biocatalysis and the utility of conceptualizing metabolism as distinct modules.

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Fig. 1: Modular approach to produce diverse polyamines in yeast.


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Correspondence to Hal S. Alper.

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The authors declare no competing interests.

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Reed, K.B., Alper, H.S. Modular biocatalysis for polyamines. Nat Catal 4, 449–450 (2021).

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