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BIOCATALYSIS

Enzymes for amino acid synthesis by design

Creating enzymes with new capabilities is a key goal for synthetic biology and sustainable chemistry. Now, computational approaches have been used to quickly achieve leaps in enzyme function, providing a versatile platform for biocatalytic hydroamination.

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Fig. 1: Computational active site redesign generates enzymes for β-amino acid synthesis.

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Correspondence to Christopher K. Prier.

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Prier, C.K. Enzymes for amino acid synthesis by design. Nat Catal 4, 348–349 (2021). https://doi.org/10.1038/s41929-021-00622-0

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