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SYNTHETIC BIOLOGY

CO2 fixation gets a second chance

Synthetic metabolic pathways that circumvent photorespiration can improve crop growth. Now, an efficient photorespiration bypass with a new-to-nature carboxylation step has been engineered and demonstrated in vitro.

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Fig. 1: Realizing the tartronyl-CoA pathway.

References

  1. Hafner, J., MohammadiPeyhani, H., Sveshnikova, A., Scheidegger, A. & Hatzimanikatis, V. ACS Syn. Biol. 9, 1479–1482 (2020).

    Article  CAS  Google Scholar 

  2. South, P. F., Cavanagh, A. P., Liu, H. W. & Ort, D. R. Science 363, eaat9077 (2019).

    Article  CAS  Google Scholar 

  3. Shih, P. M., Zarzycki, J., Niyogi, K. K. & Kerfeld, C. A. J. Biol. Chem. 289, 9493–9500 (2014).

    Article  CAS  Google Scholar 

  4. Trudeau, D. L. et al. Proc. Natl Acad. Sci. USA 115, E11455–E11464 (2018).

    Article  CAS  Google Scholar 

  5. Scheffen et al. Nat. Catal. https://doi.org/10.1038/s41929-020-00557-y (2020).

  6. Schwander, T., Schada von Borzyskowski, L., Burgener, S., Cortina, N. S. & Erb, T. J. Science 354, 900–904 (2016).

    Article  CAS  Google Scholar 

  7. Waldrop, G. L., Holden, H. M. & St Maurice, M. Protein Sci. 21, 1597–1619 (2012).

    Article  CAS  Google Scholar 

  8. Janasch, M., Asplund-Samuelsson, J., Steuer, R. & Hudson, E. P. J. Exp. Bot. 70, 973–983 (2019).

    CAS  PubMed  Google Scholar 

Download references

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Correspondence to Elton P. Hudson.

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Janasch, M., Hudson, E.P. CO2 fixation gets a second chance. Nat Catal 4, 94–95 (2021). https://doi.org/10.1038/s41929-021-00581-6

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