ARTIFICIAL ENZYMES

A single amino acid enzyme

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Enzymes require many, often hundreds, of amino acid residues arranged in a protein fold to promote catalysis. Now, self-assembly of a single amino acid — phenylalanine — in the presence of zinc is shown to form supramolecular structures that promote hydrolysis better than natural enzymes on a weight basis.

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Correspondence to Olga V. Makhlynets or Ivan V. Korendovych.

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Makhlynets, O.V., Korendovych, I.V. A single amino acid enzyme. Nat Catal 2, 949–950 (2019) doi:10.1038/s41929-019-0379-3

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