Fusion systems have been designed that link enzymes to cofactors and immobilization modules through appropriate synthetic spacers. These modular biocatalysts (assembling catalysis, cofactor provision/regeneration and assisted immobilization) are suited to heterogeneous biocatalysis systems and can be efficiently used in continuous flow reactors.
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Contente, M.L., Molinari, F. Let’s stick together for continuous flow biocatalysis. Nat Catal 2, 951–952 (2019). https://doi.org/10.1038/s41929-019-0363-y
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DOI: https://doi.org/10.1038/s41929-019-0363-y
