This year marks a century since the pioneering work leading to what is now known as the Rosenmund reduction. We celebrate this landmark, reflecting upon the evolution of synthetic methodologies for reductive aldehyde synthesis from carboxylic acid derivatives and highlighting modern, improved strategies.
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Iosub, A.V., Wallentin, CJ. & Bergman, J. Celebrating 100 years of the Rosenmund reaction. Nat Catal 1, 645–648 (2018). https://doi.org/10.1038/s41929-018-0143-0
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DOI: https://doi.org/10.1038/s41929-018-0143-0