Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

SUPRAMOLECULAR CATALYSIS

Complex terpenes in one pot

The chemical synthesis of natural products, such as sesquiterpenes, is a daunting task due to their complexity and precise functionalization, and multiple synthetic and purification steps that reduce overall yields are usually required. Now, a highly efficient alternative approach using supramolecular chemistry has been proposed by Tiefenbacher and co-workers.

This is a preview of subscription content, access via your institution

Access options

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: In-capsule synthetic approach.

References

  1. Baran, P. S. J. Am. Chem. Soc. 140, 4751–4755 (2018).

    Article  CAS  PubMed  Google Scholar 

  2. Clardy, J. & Walsh, C. Nature 432, 829–837 (2004).

    Article  CAS  PubMed  Google Scholar 

  3. Christianson, D. W. Chem. Rev. 117, 11570–11648 (2017).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Magnard, J.-L. et al. Science 349, 81–83 (2015).

    Article  CAS  PubMed  Google Scholar 

  5. Aizpurua-Olaizola, O. et al. J. Nat. Prod. 79, 324–331 (2016).

    Article  CAS  PubMed  Google Scholar 

  6. Nicolaou, K. C. et al. Nature 367, 630–634 (1994).

    Article  CAS  PubMed  Google Scholar 

  7. Zhang, Q., Rinkel, J., Goldfuss, B., Dickschat, J. S. & Tiefenbacher, K. Nat. Catal. https://doi.org/10.1038/S41596-018-0115–4 (2018).

  8. Zhang, Q. & Tiefenbacher, K. Nat. Chem. 7, 197–202 (2015).

    Article  CAS  PubMed  Google Scholar 

  9. Sobti, R. R. & Dev, S. Tetrahedron Lett. 8, 2893–2895 (1967).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Dan Thomas Major.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Major, D.T. Complex terpenes in one pot. Nat Catal 1, 567–568 (2018). https://doi.org/10.1038/s41929-018-0130-5

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41929-018-0130-5

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing