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CO2 REDUCTION

Fe4S4 clusters as small molecule catalysts

Iron–sulfur metalloproteins are widespread and efficient catalysts for multielectron reduction of small molecules. Now, research shows that simple Fe4S4 cofactors and related complexes can perform effective reductive chemistry producing small hydrocarbons from CO2 and CO.

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Fig. 1: Crystal structure of NifH (PDB code 1G5P)5 with subunit α in green and subunit β in blue.

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Correspondence to Louis Noodleman.

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Noodleman, L. Fe4S4 clusters as small molecule catalysts. Nat Catal 1, 383–384 (2018). https://doi.org/10.1038/s41929-018-0099-0

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