Table 2 Comparative IHC and FISH analysis of anti-PTEN mAb using a panel of FFPE prostate carcinomas

From: Precise definition of PTEN C-terminal epitopes and its implications in clinical oncology

    FISH− . FISH+ . FISH++a.
mAb neg/posb %neg neg pos neg pos neg pos
6H2.1 62/19 76.5 8 0 12 4 42 15
SP218 50/31 61.7 8 0 11 5 31 26
17.A 41/40 49.4 3 5 7 9 31 26
Y184 33/48 40.7 5 3 4 12 24 33
138G6 45/36 55.6 7 1 9 7 29 28
D4.3 42/39 51.8 6 2 8 8 27 30
  1. aNo PTEN signal; +, 1 PTEN signal; ++, 2 PTEN signals
  2. bNumber of negative/positive samples for IHC staining