Fig. 3 | npj Precision Oncology

Fig. 3

From: Precise definition of PTEN C-terminal epitopes and its implications in clinical oncology

Fig. 3

Reactivity of anti-PTEN mAb with PTEN variants containing amino acid substitutions at PTEN C-terminal tail. a Reactivity of anti-PTEN mAb with Ala-substitution mutations at PTEN C-terminus, as in Fig. 1. Detection of GAPDH with anti-GAPDH antibody is shown as a control. Ø, empty vector. b, c Reactivity of anti-PTEN mAb with amino acid substitutions mimicking phosphorylation or acetylation at PTEN C-terminus, as in Fig. 1. Both immunoblot images (b) and quantification of the relative mAb reactivity (c) (mean ± s.d. from two independent experiments) is shown

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