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Reproductive biology

ELVAs: The new ‘super-organelles’ of the oocyte

Omne vivum ex ovo — Every living thing comes from an egg. However, keeping eggs healthy and competent to form viable embryos is not an easy task for every organism. A recent paper describes an elegant mechanism utilised by mammalian eggs to manage possibly toxic protein aggregates.

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Fig. 1: ELVAs store or degrade protein aggregates depending on the female mouse germ-cell maturation state.

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Correspondence to Helena Fulka.

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Fulka, H. ELVAs: The new ‘super-organelles’ of the oocyte. Lab Anim 53, 133–134 (2024). https://doi.org/10.1038/s41684-024-01379-2

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