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Humane endpoints, defined

Animals used in biomedical research may experience pain or distress as part of the experimental protocol. By implementing humane endpoints, pain or distress can be prevented or alleviated whilst still meeting scientific aims and objectives. We invited experts from Arizona State University (Samantha Sullivan) and Loma Linda University (Obed Rutebuka), along with USDA and OLAW representatives (Louis DiVincenti and Axel Wolff), to respond to a scenario about the importance of defining humane endpoints in research protocols.

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References

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Acknowledgements

OLAW would like to acknowledge Neera Gopee (Associate Director for Animal Welfare Policy), Jane Na (Director, Division of Assurances), Brent Morse (Director, Division of Compliance Oversight) and Nicolette Petervary (Director, Division of Compliance Oversight) for their contribution to the preparation of the response.

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Correspondence to Lauren Danridge.

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The authors declare no competing interests.

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Disclaimer The views expressed in “A word from OLAW and USDA” represent the positions of OLAW/NIH and USDA, respectively, but the remainder of the contributions in this article do not represent official support or an endorsement by NIH, USDA, or any government agency.

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Danridge, L., Greer, B., Sullivan, S. et al. Humane endpoints, defined. Lab Anim 53, 123–125 (2024). https://doi.org/10.1038/s41684-024-01378-3

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