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The well-built research question

How to reduce animal numbers and increase the information content of animal-based studies. A ‘well-built’ research question turns the research hypothesis into an actionable, focused, and testable plan of action.

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Fig. 1: System diagram for the ‘well-built’ research question PICOT.


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Correspondence to Penny Reynolds.

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Reynolds, P. The well-built research question. Lab Anim 52, 221–223 (2023).

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