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Know Your Model: When parental origin matters

Lab Animal volume 49, pages 161–162 (2020)Cite this article

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Differential gene expression based on the parental origin can have a big impact on phenotype

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Fig. 1: Paternal vs. maternal inheritance influences Ndntm1Stw expression in mouse models of Prader-Willi syndrome.

References

  1. Monk, D., Mackay, D. J. G., Eggermann, T., Maher, E. R. & Riccio, A. Nat. Rev. Genet. 20, 235–248, https://doi.org/10.1038/s41576-018-0092-0 (2019).

    Article  CAS  PubMed  Google Scholar 

  2. Gérard, M., Hernandez, L., Wevrick, R. & Stewart, C. L. Nat Genet. 23, 199–202, https://doi.org/10.1038/13828 (1999).

    Article  PubMed  Google Scholar 

  3. Horsthemke, B. & Wagstaff, J. Am J Med Genet Part A. 146, 2041–2052, https://doi.org/10.1002/ajmg.a.32364 (2008).

    Article  CAS  Google Scholar 

  4. Szabó, P. & Mann, J. R. Development. 120, 1651–1660, http://www.ncbi.nlm.nih.gov/pubmed/8050371 (1994). Accessed March 3, 2020.

    PubMed  Google Scholar 

  5. Steshina, E. Y., Carr, M. S., Glick, E. A., Yevtodiyenko, A., Appelbe, O. K. & Schmidt, J. V. BMC Genet. 7, 44, https://doi.org/10.1186/1471-2156-7-44 (2006).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Takahashi, N., Okamoto, A. & Kobayashi, R. et al. Hum Mol Genet. 18, 1879–1888, https://doi.org/10.1093/hmg/ddp108 (2009).

    Article  CAS  PubMed  Google Scholar 

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Acknowledgements

MGD is supported by program project grant HG000330 from the National Human Genome Research Institute (NHGRI) of the National Institutes of Health (NIH).

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  1. Mouse Genome Informatics, The Jackson Laboratory, Bar Harbor, ME, USA

    Susan M. Bello, Michelle N. Perry & Cynthia L. Smith

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  1. Susan M. Bello
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  2. Michelle N. Perry
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Correspondence to Susan M. Bello.

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Bello, S.M., Perry, M.N. & Smith, C.L. Know Your Model: When parental origin matters. Lab Anim 49, 161–162 (2020). https://doi.org/10.1038/s41684-020-0550-0

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