The microbiome many consist of small microorganisms, but it can make a big impact on experimental results. Although its exact role is still being teased apart, there are ways researchers can be mindful of the microbial variable in their mouse studies.
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Katsnelson, A. Minding the microbiome of your mice. Lab Anim 48, 313–315 (2019). https://doi.org/10.1038/s41684-019-0424-5