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GUT MICROBIOTA

Outrunning Salmonella – the role of endogenous Enterobacteriaceae in variable colonization resistance

The mammalian gut microbiota confers colonization resistance against pathogenic bacteria. Specific pathogen-free C57BL/6 mice from different vendors are variably resistant to oral non-typhoidal Salmonella infection. New work shows that differences in endogenous Enterobacteriaceae determine this phenotypic variability.

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Correspondence to Siegfried Hapfelmeier.

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Fig. 1: Protective Enterobacteriaceae bloom.