The mammalian gut microbiota confers colonization resistance against pathogenic bacteria. Specific pathogen-free C57BL/6 mice from different vendors are variably resistant to oral non-typhoidal Salmonella infection. New work shows that differences in endogenous Enterobacteriaceae determine this phenotypic variability.
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Hapfelmeier, S. Outrunning Salmonella – the role of endogenous Enterobacteriaceae in variable colonization resistance. Lab Anim 48, 203–204 (2019). https://doi.org/10.1038/s41684-019-0327-5
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DOI: https://doi.org/10.1038/s41684-019-0327-5
