Animal disease models

Modeling genetic diversity in Alzheimer’s disease

There are a number of genetic factors that contribute to Alzheimer’s disease in people. A new mouse model attempts to better capture that variability.

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Fig. 1: Schematics of the AD model cross with BXD Strains (A) and phenotyping process (B).

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Correspondence to Katherine R. Sadleir.

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Sadleir, K.R., Vassar, R. Modeling genetic diversity in Alzheimer’s disease. Lab Anim 48, 87–88 (2019). https://doi.org/10.1038/s41684-019-0248-3

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