Correspondence | Published:

Harm-Benefit Analysis: opportunities for enhancing ethical review in animal research

Lab Animalvolume 47pages5758 (2018) | Download Citation

Subjects

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    Home Office. Guidance on the Operation of the Animals (Scientific Procedures) Act 1986 (Home Office, London, 2014).

  2. 2.

    Brønstad, A. et al. Current concepts of harm–benefit analysis of animal experiments–report from the AALAS–FELASA working group on harm–benefit analysis–part 1. Laboratory Animals 50, 1–20 (2016).

  3. 3.

    Laber, K. et al. Recommendations for addressing harm–benefit analysis and implementation in ethical evaluation–report from the AALAS–FELASA working group on harm–benefit analysis–part 2. Laboratory Animals 50, 21–42 (2016).

  4. 4.

    European Commission. National Competent Authorities for the implementation of Directive 2010/63/EU on the Protection of Animals Used for Scientific Purposes: Working Document on Project Evaluation and Retrospective Assessment (2013).

  5. 5.

    OIE. Terrestrial Animal Health Code, Chapter 7.8, Use of animals in Research and Education (Office International des Epizooties, 2016).

  6. 6.

    CIOMS-ICLAS. International Guiding Principles for Biomedical Research Involving Animals (Council for International Organizations of Medical Sciences - International Council for Laboratory Animal Science, 2012).

  7. 7.

    Pound, P. & Blaug, R. Transparency and public involvement in animal research. ATLA 44, 167–173 (2016).

  8. 8.

    Haraway, D. When Species Meet (University of Minnesota Press, 2008) p.87.

  9. 9.

    AMS. Reproducibility and reliability of biomedical research: improving research practice (The Academy of Medical Sciences, London, 2015).

  10. 10.

    Walport, M. Animal Research: Then and Now. Online seminar. (2016).

Download references

Acknowledgements

The ASC Harm–Benefit Analysis subgroup was established in autumn 2014. Its members are: Professor Gail Davies (ASC, Chair of the subgroup); Huw Golledge (ASC); Penny Hawkins (ASC); Anna Rowland (ASC); Sarah Wolfensohn (ASC); Jane Smith (Boyd Group, advice and report drafting); and Dominic Wells (Animals in Science Group at the Royal Society of Biology, advisory input). The subgroup was supported throughout their work by Dr Jo Wallace and Caroline Wheeler from the Home Office Science Secretariat. Gabrielle King contributed to research on the evaluation of benefits at the University of Exeter.

Author information

Affiliations

  1. University of Exeter, Exeter, UK

    • Gail F. Davies

Authors

  1. Search for Gail F. Davies in:

Corresponding author

Correspondence to Gail F. Davies.

Electronic supplementary material

  1. Review of harm-benefit analysis in the use of animals in research

    Report of the Animals in Science Committee Harm-Benefit

About this article

Publication history

Published

DOI

https://doi.org/10.1038/s41684-018-0002-2

Newsletter Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing