Retraction of: Scientific Reports https://doi.org/10.1038/s41598-021-03727-5, published online 20 December 2021


The Editors have retracted this Article.


After publication of this Article concerns were raised regarding the design of the study and the robustness of its central conclusions. Post-publication peer review has confirmed that:

  • there is insufficient justification for the grouping of the patients who belong to clinically heterogeneous cohorts with multiple different psychiatric disease presentations;

  • the study lacks objective outcome measures; and

  • there are concerns about the validity of the therapeutic intervention tested—specifically that Tenoten contains antibodies diluted beyond the point at which any active molecules are expected to be present and there is no molecular analysis to support the presence of molecules at these dilutions


The Editors therefore no longer have confidence in the conclusions presented.


Vladimir Anatolevich Parfenov, Dina Rustemovna Khasanova, Pavel Rudolfovich Kamchatnov and Alexey Borisovich Glazunov disagree with this retraction. Enver Ibragimovich Bogdanov, Tatiana Markovna Lokshtanova, Aleksandr Vitalevich Amelin, Natalya Nikolaevna Maslova, Nataliia Vyacheslavovna Pizova, Galina Nikolaevna Belskaya, Evgeny Robertovich Barantsevich, Gulsum Abdurahmanovna Duchshanova, Saltanat Ualihanovna Kamenova and Oleg Vladimirovich Kolokolov did not respond to correspondence from the Editors about this retraction.