Table 1 Baseline characteristics of LVAD cohort.

From: Association between early ventricular arrhythmias and mortality in destination vs. bridge patients on continuous flow LVAD support

  Overall cohort (n = 341) DT group (n = 155) BTT group (n = 186) P value Early VA (n = 128) No early VA (n = 213) P value
Age (years ± SD) 58.1 ± 14.1 64.4 ± 12.9 53.2 ± 12.8  < 0.001 60.3 ± 11.7 57.0 ± 15.1 0.027
Male gender n (%) 278 (81.5%) 125 (80.6%) 153 (82.3%) 0.76 104 (81.2%) 174 (81.7%) 0.92
Caucasian n (%) 270 (86.5%) 125 (88.0%) 145 (85.3%) 0.55 104 (88.9%) 166 (85.1%) 0.64
ICM n (%) 179 (52.5%) 79 (51.0%) 100 (53.8%) 0.65 75 (58.6%) 104 (48.8%) 0.08
Pre-LVAD VA n (%) 173 (51.3%) 71 (46.1%) 102 (54.8%) 0.051 80 (63.0%) 93 (43.7%)  < 0.001
LVAD type
Heartmate II 234 (68.2%) 110 (71.9%) 124 (66.3%) 0.26 92 (71.9%) 142 (67.0%) 0.21
Heartmate III 57 (16.6%) 25 (16.3%) 30 (16.0%)   15 (11.7%) 40 (18.9%)  
HeartWare 52 (15.2%) 18 (11.8%) 33 (17.6%)   21 (16.4%) 30 (14.1%)  
INTERMACS ≤ 2 n (%) 222 (65.5%) 100 (64.9%) 122 (65.9%) 0.80 84 (65.6%) 138 (65.4%) 0.97
Mean BMI (n ± SD) 29.0 ± 5.8 28.5 ± 6.0 29.5 ± 5.6 0.01 30.0 ± 5.6 28.5 ± 5.8 0.017
CAD n (%) 251 (74.5%) 119 (76.8%) 132 (72.5%) 0.43 97 (77.0%) 154 (73.0%) 0.41
PAD n (%) 57 (17.0%) 36 (23.4%) 21 (11.5%) 0.001 14 (11.1%) 43 (20.5%) 0.027
CVA/TIA n (%)? 72 (21.1%) 31 (20.0%) 41 (22.0%) 0.23 44 (34.9%) 64 (30.5%) 0.40
MI n (%) 112 (33.2%) 51 (32.9%) 61 (33.5%) 0.84 41 (32.5%) 71 (33.6%) 0.83
CABG n (%) 54 (16.0%) 29 (18.7%) 25 (13.7%) 0.16 21 (16.7%) 33 (15.6%) 0.80
Prior sternotomy n (%) 130 (37.8%) 62 (40.5%) 65 (35.6%) 0.35 55 (42.6%) 75 (34.9%) 0.15
Prior circulatory support n (%) 48 (13.9%) 17 (11.1%) 31 (16.2%) 0.17 24 (18.6%) 24 (11.2%) 0.08
DM n (%) 146 (43.3%) 76 (49.0%) 70 (38.5%) 0.07 58 (46.0%) 88 (41.7%) 0.44
HTN n (%) 171 (50.1%) 78 (50.3%) 93 (51.1%) 0.84 68 (54.0%) 103 (48.8%) 0.36
HPL n (%) 132 (39.2%) 65 (41.9%) 67 (36.8%) 0.30 51 (40.5%) 81 (38.4%) 0.70
AF n (%) 134 (39.8%) 76 (49.0%) 58 (31.9%) 0.001 50 (39.7%) 84 (39.8%) 0.98
ICD n (%) 228 (67.7%) 107 (69.0%) 121 (66.5%) 0.65 92 (73.0%) 136 (64.5%) 0.10
COPD n (%) 70 (20.1%) 40 (25.8%) 30 (16.5%) 0.043 27 (21.4%) 43 (20.4%) 0.82
Mean GFR (n ± SD) 59.8 ± 20.7 56.4 ± 19.7 62.8 ± 21.1 0.003 56.5 ± 18.5 61.8 ± 21.7 0.021
Pre-EF (n ± SD) 19.9 ± 8.2 19.6 ± 8.3 20.1 ± 8.2 0.67 19.8 ± 7.8 19.8 ± 8.5 0.99
Pre-LVEDD (n ± SD) 7.0 ± 1.0 6.8 ± 1.1 7.2 ± 1.0 0.006 7.05 ± 1.0 6.95 ± 1.0 0.42
Pre-LVESD (n ± SD) 6.3 ± 1.1 6.1 ± 1.1 6.4 ± 1.1 0.008 6.32 ± 1.0 6.23 ± 1.1 0.50
  1. AF atrial fibrillation, BMI body mass index, BTT bridge to transplant, CABG coronary artery bypass graft, CAD coronary artery disease, COPD chronic obstructive pulmonary disease, CVA cerebrovascular accident, DM diabetes mellitus, DT destination therapy, GFR glomerular filtration rate, HPL hyperlipidemia, HTN hypertension, ICD Implantable cardioverter-defibrillator, ICM ischemic cardiomyopathy, INTERMACS Interagency Registry for Mechanically Assisted Circulatory Support, LVAD left ventricular assist device, LVEDD left ventricular end-diastolic diameter, LVESD left ventricular end-systolic diameter, MI myocardial infarction, PAD peripheral artery disease, TIA transient ischemic attack, VA ventricular arrhythmia.
  2. P values presented in bold are statistically significant (<0.05).