Table 3 Unadjusted independent variables of appendicitis in 51 children with appendicitis and 82 healthy controls.

From: Associations of hair cortisol concentrations with paediatric appendicitis

  Appendicitis (n = 51) Controls
(n = 82)
OR (95% CI) p value
Age (years) 9 (1–13) 6 (1–15) 1.11 (1.02–1.22) 0.021
Sex (Male) 26 (51%) 38 (41%) 0.68 (0.34–1.37) 0.284
Viral infections < 6 m 2 (0–5) 2 (0–8) 0.94 (0.74–1.19) 0.600
Bacterial infections < 6 m 0 (0–2) 0 (0–1) 1.16 (0.30–4.48) 0.825
Surgery < 6 m 0 (0%) 2 (2%)
Serious illness < 6 m 5a (10%) 1b (1%) 8.8 (0.998–77.67) 0.050
Serious life events < 6 m 4c (8%) 0 (0%)
Season     0.021
Winter 8 (16%) 25 (30%) 0.58 (0.23–1.51) 0.264
Spring 9 (18%) 2 (2%) 8.18 (1.62–41.26) 0.011
Summer 12 (24%) 15 (18%) 1.45 (0.58–3.65) 0.425
Autumn 22 (43%) 40 (49%) 1  
HCC 0–3 months (pg/mg) 21.3 (6.7–373.7) 24.1 (6.0–606.7) 0.89 (0.37–2.15) 0.80
HCC 4–6 months (pg/mg) 13.7 (4.1–1524.5) 25.1 (5.8–979.12) 0.46 (0.19–1.10) 0.081
Difference in HCC (%) 123 (16–441) 100 (15–182) 7.52 (2.49–22.67) 0.001
  1. Values presented as median (min–max) or as absolute number (percentage of patients).
  2. M: male, F: female. n = 106 (66 controls, 40 cases) for HCC 4–6 months and difference in HCC.
  3. a) 2 fractures, 1 thyrotoxicosis, 1 severe autism, 1 severe ADHD; b) urinary tract disorder with long-term catheter; c) 1 with severely depressed father, 2 with domestic abuse, 1 with loss of close relative.