Table 1 Patients’ clinical characteristics and treatment details.

From: First Asian population study of stereotactic body radiation therapy for ventricular arrhythmias

Variable Patient 1 Patient 2 Patient 3 Patient 4 Patient 5 Patient 6 Patient 7
Clinical characteristics
Age (years) 58 56 49 47 23 72 80
Sex Female Male Male Male Male Male Male
Indication Ischemic cardiomyopathy Dilated cardiomyopathy Frequent PVCs Dilated cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy Hypertrophic cardiomyopathy Dilated cardiomyopathy
LVEF before treatment (%) 45 20 66 30 69 42 43
Anti-arrhythmic drugs Amiodarone BB + amiodarone BB + mexiletine BB + amiodarone BB + amiodarone BB + amiodarone BB + amiodarone
Amiodarone dosage (mg/d) 300 400 0 100 400 400 200
No. of catheter ablations 1 0 2 1 4 2 2
No. of episodes of VT at 3 months before treatment 34 14 PVC 35% 3 6 3 31
No. of ICD shocks 5 3 1 6 2 8
Treatment
Target region Inferoposterior wall Anterior wall Basal anteroseptum RVOT RV basal septum Apex Anteroseptum to inferoseptum
Volume (cm3)
ITV 15.4 40.9 9.4 4.6 11.5 35.3 33.5
PTV 52.1 80.5 23.9 14.4 34.4 83.4 92.6
Time (min) 12.7 17.3 14.4 9.2 10.9 12.5 12.5
No. of episodes of VT after treatment 9 1 PVC 0.2% 0 13 5 0
No. of ICD shocks after treatment 1 0 0 0 0 0
Time to recurrence (days) 245 366 0 105   
LVEF after treatment (%) 33 22 72 68 65 42 33
  1. PVC premature ventricular contraction, BB beta-blocker, LVEF left ventricular ejection fraction, VT ventricular tachycardia, ICD implantable cardioverter-defibrillator, RVOT right ventricular outflow tract, RV right ventricular, ITV internal target volume, PTV planning target volume.