Table 1 Clinicopathological characteristics of study patients.

From: Combination of lymphocyte count and albumin concentration as a new prognostic biomarker for rectal cancer

Variables n = 240, median [range], n(%)
Age 66 [21–90]
Sex
Male 163 (68)
Female 77 (32)
Tumor location
Ra 122 (51)
Rb-P 118 (49)
cStage
II 73 (30)
III 167 (70)
CEA 16.4 ± 9.7
Preoperative treatment
none 170 (71)
nCRT 24 (10)
NAC 46 (19)
Surgical procedure
LAR 158 (66)
ISR 32 (13)
APR 39 (16)
TPE 4 (2)
Hartmann 7 (3)
Surgical approach
Laparoscopic 201 (84)
Robot 23 (10)
Open 10 (4)
Conversion 6 (2)
pT classification
pT1/T2 75 (31)
pT3/T4 165 (69)
pN classification
negative 157 (65)
positive 83 (35)
Histology
well/mod 223 (93)
por/muc 16 (7)
Adjuvant Chemotherapy 107 (45)
Inflammation parameters
Neutrophil (/µL) 3467 [768–13,275]
Lymphocyte (/µL) 1472 [67.2–28,079]
Platelet (/µL) 224,500 [16,000–523,000]
Monocyte (/µL) 341 [151–1344]
Albumin (g/dL) 4.0 [2.0–4.9]
CRP (mg/dL)
 0 57 (24)
 0 < , ≤ 0.2 124 (52)
 0.2 < , ≤ 1.0 45 (19)
 1.0 <  14 (5)
Combinations
NLR 2.31 [0.15–64.4]
PLR 140 [10–286]
PAR 56,300 [4000–223,000]
LMR 4.53 [0.24–81.06]
MAR 85.2 [32.7–413.3]
NP 767,460 [20,748–5,408,480] (× 103)
LA 5950 [275.5–10,951]
NM 1,219,048 [227,697–13,069,600]
MP 76,682 [3057–322,560] (× 103)
GPS
0 224 (93)
1 6 (3)
2 10 (4)
SIS
0 66 (28)
1 115 (48)
2 59 (24)
  1. CEA carcinoembryonic antigen, nCRT neoadjuvant chemoradiotherapy, NAC neoadjuvant chemotherapy, LAR low anterior resection, ISR intersphincteric resection, APR abdominoperineal resection, TPE total pelvic exenteration, well/mod well-differentiated/moderately-differentiated, por/muc poorly-differentiated/mucinous, CRP C-reactive protein, NLR neutrophil-to-lymphocyte ratio, PLR platelet-to-lymphocyte ratio, PAR platelet-to-albumin ratio, LMR lymphocyte-to-monocyte ratio, MAR monocyte-to-albumin ratio, NP neutrophil × platelet, LA lymphocyte × albumin, NM neutrophil × monocyte, and MP monocyte × platelet, GPS Glasgow prognostic scale, SIS systemic inflammation scale.