Figure 1 | Scientific Reports

Figure 1

From: Importance of HBsAg recognition by HLA molecules as revealed by responsiveness to different hepatitis B vaccines

Figure 1

Manhattan plot from dense imputed data by applying a regression analysis with age, sex, and the number of vaccinations as covariates. Among 555 Japanese HB-vaccinated individuals with Heptavax-II, P values were calculated in a comparison (A) between poor-responders (n = 66) and responders (n = 489), and (B) between poor-responders and high-responders (n = 305) using a chi-square test for allele frequencies. Dashed lines indicate genome-wide significance levels of P = 5.0 × 10–8.

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