Figure 3 | Scientific Reports

Figure 3

From: Time-domain diffuse correlation spectroscopy (TD-DCS) for noninvasive, depth-dependent blood flow quantification in human tissue in vivo

Figure 3

Time-domain diffuse correlation spectroscopy measurement in two-layer liquid phantoms with absorption coefficient (\(\mu _a = 0.06\,{{\text{cm}}}^{-1}\)) and variable reduced scattering (\(\mu _s^{\prime } = 7.5, 10.0,\) and \(12.5\,{{\text{cm}}}^{-1}\)). (ac) Estimated TOF-resolved autocorrelation decays and the diffusion coefficients (df). The standard model provides a constant slope of the ACF decays, and thus is incapable to distinguish flows in different layers (d). On contrary, the fast component of the novel model changes at 600 ps (b), which allows to clearly separate the depth-dependent diffusion coefficients (e). The slow component of the novel model senses the top layer along different TOFs by providing a uniform slope of ACF decay (c), and a constant diffusion coefficient (f) close to the value estimated by the fast component at early TOFs (e).

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