## Abstract

Spontaneous collapse models of state vector reduction represent a possible solution to the quantum measurement problem. In the present paper we focus our attention on the Ghirardi–Rimini–Weber (GRW) theory and the corresponding continuous localisation models in the form of a Brownian-driven motion in Hilbert space. We consider experimental setups in which a single photon hits a beam splitter and is subsequently detected by photon detector(s), generating a superposition of photon-detector quantum states. Through a numerical approach we study the dependence of collapse times on the physical features of the superposition generated, including also the effect of a finite reaction time of the measuring apparatus. We find that collapse dynamics is sensitive to the number of detectors and the physical properties of the photon-detector quantum states superposition.

## Introduction

A number of interpretations/extensions of quantum mechanics have been proposed to attempt to solve the quantum measurement problem. On the one hand, there, for instance, are decoherence theories: see Ref.^{1} for a review. On the other hand, various extensions of quantum mechanics have been developed that lead to dynamical models for the collapse of the wave function. Stochastic processes modelling the spontaneous collapse of the state of the quantum system were first proposed in Ref.^{2}. This is the so called GRW theory, which involves discontinuous stochastic processes^{3,4}. Continuous models have been also been devised, in which the spontaneous collapse of the quantum state is realized in the form of a continuous stochastic process in Hilbert space. A number of different versions of such models have been put forward. See, for example, Refs.^{2,5,6,7,8,9,10,11,12,13,14,15,16,17}.

The two families of processes are strictly connected. Actually, in Ref.^{18} it has been shown that discontinuous processes, in a proper infinite frequency limit, are equivalent to appropriate continuous ones. In all these process in Hilbert space a set of *physical quantities* (observables) appears, represented by the corresponding set of selfadjoint operators. The processes act inducing the *sharpening * of the distribution of values of those quantities around a stochastically chosen centre. In Ref.^{3} it has been shown that the physical effect of the stochastic processes depends on the choice of observables that are being *sharpened* and not on the details of the sharpening procedure.

In this work we focus the attention on the position of a macroscopic/mesoscopic pointer as the observable that is going to undergo the sharpening processes. In particular, we examine two types of experimental setups, in which a superposition of macro(meso)scopic states is generated. By using a continuous model for the collapse, we show how the collapse times depends both on the number of detectors and, crucially, on the physical features of the superposition in the measured state. By using the connection between the continuous process and the GRW model, we provide also a clear physical interpretation of the parameters of the model. This type of studies represent an essential step to guide actual experimental effort, in order to be able to impose limits on the values of the parameters and either confirm or disprove the spontaneous collapse models.

The paper is organised as follows. In “Hitting and continuous processes” section the main features of the two approaches are recalled, together with their relationship. In “Single detector” section the continuous process is specialised to an experimental setup in which a single photon is sent to a beam splitter creating a superposition of transmitted/reflected photon states, and the photon is either detected or not detected by a single-photon detector placed in the transmission region. “Two detectors” section is devoted to the analysis of the setup in which a second single-photon detector is added in the reflection region. In “The system/detector interaction and its interplay with the stochastic process” section the photon/detector interaction is modelled and taken into account in the measurement dynamics, together with its interplay with the stochastic reduction process. In “Numerical results” section a number numerical simulations are shown and commented. In “Conclusions” section some conclusions are drawn.

## Hitting and continuous processes

Let the set of compatible quantities characterizing the discontinuous stochastic process be

and the sharpening action be given by the operator

The parameter \( \alpha \) rules the accuracy of the sharpening and \(\varvec{a}_i \) is the centre of the *i*-th hitting. It is assumed that the hittings occur randomly in time, distributed according to a Poisson law with frequency \(\lambda \).

The sharpening operator for the *i*-th hitting \(S_i\) acts on the normalized state vector \(| {\psi _t} \rangle \) giving the state vector \(| {\varphi _{i,t}} \rangle \), which can be recast in a normalized vector \(| {\psi '_{i,t}} \rangle \):

The probability that the hitting takes place around \(\varvec{a}_i \) is

Actually, it turns out that the effectiveness of the discontinuous process depends on \(\alpha \) and \(\lambda \) only through their product.

The continuous process based on the same quantities \({\hat{\varvec{A}}} \equiv \{ {{\hat{A}}}_m\}_{m=1}^K\) is ruled by the Itô stochastic differential equation

where

and

The parameter \(\gamma \) sets the effectiveness of the process.

In Refs.^{3,18} it has been shown that, by taking the infinite frequency limit of the discontinuous process (3) and (4) with the prescription

one gets the continuous process of Eq. (5). As a consequence it becomes apparent that, for \(t \rightarrow \infty \), the continuous process drives the state vector to a common eigenvector of the operators \(\hat{\varvec{A}}\). The probability of a particular eigenvector \(| {\varvec{a}_r} \rangle \) is given by \(\vert \langle {\varvec{a}_r} | {\psi _0} \rangle \vert ^2\), for the generic state vector \(| {\psi _0} \rangle \) at a given arbitrary initial time.

## Single detector

Consider the experimental setup depicted in Fig. 1, in which a single photon state hits a beam splitter (BS), a superposition of \(| {\gamma } \rangle _R\) and \(| {\gamma } \rangle _L\) states is formed and a single photon detector (SPD) is placed in *R* position. In this case Eqs. (5)–(7) are specialized to a single operator \({{\hat{A}}}\), namely the operator associated to the “pointer position” (more on this later).

We indicate with \(\vert c_{R,L}\vert ^2\) the transmission and reflection coefficients of the BS, respectively. Therefore, in the *photon + detector* Hilbert space one has that the Schrödinger evolution generates the superposition

where \(| {D^{(0,+)}} \rangle \) are the SPD states that correspond to SPD “ready” or “clicked”, respectively, and \(\vert c_L \vert ^2 + \vert c_R \vert ^2 = 1\). The operator associated to the pointer position can be represented as

where \(a_{0,+}\) are the pointer position eigenvalues. Eqs. (5)–(7) become

The time evolution of the coefficients of the superposition, \(c_{R,L}\), as due to the stochastic process, can be obtained by projecting \( | {\psi (t +{{\mathrm{d}}}t)} \rangle \) onto \(| {\psi _{R,L}} \rangle \), namely

where

and \(K_{0,+} (t) = a_{0,+} - J(t)\). Since \(K_i(t)\) (and hence \(L_i(t)\)) is invariant under translation of the system of eigenvalues \(a_i\), without loss of generality one can take \(a_0 = 0 \) and \(a_+ = a\), obtaining

from which

Since, according to Eq. (14),

one has, by squaring eq. (18) and taking into account the Itô lemma, that:

The stochastic factor \(L^2_{R,L} (t)\) of Eq. (20) can be generated numerically in each step in *dt* by extracting a gaussian random number \({\mathrm{d}}B\), according to the statistics of Eq. (12), and iteratively inserting it into Eq. (19) to produce the “path” followed by \(\vert c_{R,L} \vert ^2\) during the reduction process.

## Two detectors

When considering the experimental setup described in Fig. 2, where a second (and, for the sake of simplicity, identical) SPD has been added in *L* position, the Schrödinger evolution generates, in the *photon + detectors* Hilbert space, the superposition

where now \(D_{R,L}\) are the states of the *R* and *L* SPD, respectively, and, again, \(\vert c_L \vert ^2 + \vert c_R \vert ^2 = 1\). The operators associated to the *R* and *L* pointer position are

By following the same procedure sketched in the previous section, one obtains

from which

It is worth noticing that Eq. (27) can be rewritten as

where

is a gaussian stochastic variable obeying the statistics

## The system/detector interaction and its interplay with the stochastic process

In the previous sections the system/apparatus interactions generating the superpositions (9) and (21) have been considered “instantaneous”. Actually, any real device has a finite reaction time *T* and the dynamical development of the superpositions can be modelled by proper interaction hamiltonians (see for instance Ref.^{19}, where the von Neumann model of measurement in quantum mechanics is described in detail, and Ref.^{20} for a recent discussion about the interplay between the measurement time and the localisation process).

Considering the single detector case, the system/apparatus interactions hamiltonian can be written as

where \({{\hat{P}}}\) is the momentum operator of the pointer, *R* is defined as

the function *f* satisfies

\(\beta (t)\) is the activation function that, for the sake of simplicity, is assumed piecewise linear starting from \(t=0\) taken as the interaction initial time

and *T* is the time at which the interaction has fully developed.

The effect of the interaction hamiltonian (31) on the initial superposition

is the following: since \({{\hat{R}}} | {\gamma } \rangle _L = 0 \), the term \(c_L | { \gamma } \rangle _L | {D^{(0)}} \rangle \) is left unchanged; on the contrary, since \({{\hat{R}}} | {\gamma } \rangle _R = | {\gamma } \rangle _R\), the pointer position in the term \(c_R | { \gamma } \rangle _R | {D^{(0)}} \rangle \) is shifted from position “0” to position “*a*”, corresponding to \(c_R | { \gamma } \rangle _R | {D^{(+)}} \rangle \), linearly in the time interval \((t=0, t=T)\).

When taking into account the interaction (31), Eq. (11) becomes

Under the (very good) approximation that the stochastic process does not affect the pointer wave functions corresponding to different pointer positions, but affects only the coefficients of the superposition (\(c_{R,L}\)), Eq. (18) becomes

from which

and, analogously, Eq. (26) turns into

from which

It is worth noticing that the difference between Eqs. (20) and (28) on one side, and Eqs. (38) and (40) on the other, consists in the presence of the activation function \(\beta (t)\) in the stochastic term, and can be qualitatively understood as follows: the stochastic localization process is the more effective the more separate are the positions of the terms in the superposition. Since the interaction hamiltonian (31) generates the superposition gradually, the stochastic process starts at time \(t=0\) and becomes fully effective at time \(t=T\), when \(\beta (T) = 1\).

## Numerical results

The original choice of parameters, for a process of localisation in position space, in Ref.^{2} was

Recently, the experimental search of spontaneous X-ray emission^{21} has possibly excluded this set of paramenters. A possible choice compatible with^{21} is

that, according to Eq. (8), corresponds to

For an object of approximately 1 \(\hbox {cm}^3\) the number of elementary constituents is assumed to be \(10^{23}\). Consequently, if the dimension of the object is reduced to 1 \(\hbox {mm}^3\) one has approximately \(10^{20}\) constituents. From these considerations, in the first case one has

and in the second case

Correspondingly, it is assumed that the parameter *a* describilng the “pointer” shift in position is \(a = 1\) cm in the first case and \(a = 1\) mm in the second one.

Figure 3 shows a sample of \(10^3\) paths followed by \(\vert c_R (t) \vert ^2\) for the starting conditions \(\vert c_R \vert ^2 = 1/2, 2/3, 4/5\) and 1/20 for the case of a single detector with \(\gamma = \gamma _1\). The blue/red paths correspond to the effect of the stochastic process alone and to the combined effect of stochastic process and von Neumann activation with \(T=10^{-4}\) ns, respectively. The paths tend to converge to \(\vert c_R \vert ^2 = 1\) or \(\vert c_R \vert ^2 = 0\) with probability given by the starting condition (Born rule). For the stochastic process alone, the time scale at which the paths approach convergence is of the order of \(5 \times 10^{-5}\) ns, while in the presence of von Neumann activation the convergence is more distributed in time and becomes clear for \(t \simeq T\), as expected.

Figure 4 is the same as Fig. 3, but for \(\gamma = \gamma _2\) and \(T = 5\) ns. Now the time scale at which the paths approach convergence is of the order of 3 ns (no von Neumann activation). The lengthening of the convergence time is due to the fact that in this case the detector is smaller and hence fewer constituents contribute to the spontaneous collapse.

Figure 5 is the same as Figure 3, but for the case of two detectors. As can be seen, the convergence is more rapid than in the case of a single detector. The larger effectiveness of the localization process can be traced back to the statistical properties of the stochastic process \({\mathrm{d}}C\), whose variance is two times the variance of the individual stochastic processes \({\mathrm{d}}B\).

In all these cases *T* has been chosen larger than the typical convergence time scale; for *T* less then, or similar to, the convergence time scale the stochastic process is not affected in a significant way.

In order to better quantify the convergence properties of the processes. Figure 6 shows the number of paths that, at each time bin, reached \(\vert c_R \vert ^2 \ge 1-\varepsilon \) (blue and black histograms for von Neumann activation switched off/on, respetively) or \(\vert c_R \vert ^2 \le \varepsilon \) (green and red histograms for von Neumann activation switched off/on, respetively), with \(\varepsilon = 1/N\), *N* being the number of paths considered in the statistical sample, for the case of a single detector and \(\gamma = \gamma _2\). The integral of any single histogram represents the total number of paths arrived at convergence (Born Rule). As can be noticed by comparing same color histograms, their shape and peak position depend on the starting conditions. For instance, looking at the blue histograms (paths converging to \(\vert c_R \vert ^2 = 1\) ), the peak present for the starting condition \(\vert c_R \vert ^2 = 4/5\) tends to flatten as the initial value for \(\vert c_R \vert ^2 \) is reduced and its position shifts from about 5 to about 8 ns for the starting condition \(\vert c_R \vert ^2 = 1/20\). Qualitatively similar comments hold also for Fig. 7, where the case of two detectors is shown.

Figure 8 shows the persistence of the superposition of \(| {\psi _{R,L}} \rangle \) states. The fraction of paths with \(\varepsilon \le \vert c_R \vert ^2 \le 1-\varepsilon \) is represented as a function of time. The green and blue curves correspond to the starting conditions \( \vert c_R \vert ^2 = 1/20 \) and 1/2, respectively, without von Neumann activation. The red and black curves represent the same situation with von Neumann activation. The setup with \(\gamma = \gamma _1\) and a single detector has been chosen. As can be seen, both with and without von Neumann activation the starting condition \( \vert c_R \vert ^2 = 1/2 \) corresponds to a longer lasting superposition, while with \( \vert c_R \vert ^2 = 1/20 \) the superposition decays more rapidly. A qualitatively similar situation is found for the other setup previously considered.

At last, Fig. 9 shows the persistence of the superposition for the paths converging to \( \vert c_R \vert ^2 = 1\). The fraction of paths converging to \( \vert c_R \vert ^2 = 1\) with \(\varepsilon \le \vert c_R \vert ^2 \le 1-\varepsilon \) is represented as a function of time, the blue and green curves correspond to the starting conditions \( \vert c_R \vert ^2 = 1/2 \) and 1/20, respectively, without von Neumann activation. The black and red curves represent the same situation with von Neumann activation. The setup with \(\gamma = \gamma _1\) and a single detector has been chosen. As can be seen, both with and without von Neumann activation, for the paths converging to \( \vert c_R \vert ^2 = 1\) the superposition of \(| {\psi _{R,L}} \rangle \) states is more persistent for the starting condition \( \vert c_R \vert ^2 = 1/20\) than for \( \vert c_R \vert ^2 = 1/2\).

## Conclusions

In the present paper a detailed study of collapse dynamics as provided by GRW theory and its continuous realisations in the form of stochastic differential equations describing a Brownian-driven motion in Hilbert space has been presented. The possible effect of the finite reaction time of the apparatus has also been considered. It has been assumed that a “pointer” shifts its position by an amount *a* as a consequence of its measurement; this, of course, is not the general case, and what is the “pointer” has to be established in relation to the real physical detection and logging apparatus employed. The features of the convergence properties depend on the physical properties of the superposition state, and could be exploited to design experiments aiming at pointing out “GRW” effects.

The two elements determining the time resolution in the experiment outlined in Figs. 1 or 2 are the single photon source and the detectors. We will now briefly consider the challenges each one presents to the possibility of a an actual implementation of the proposed experiment.

A wide variety of single photon sources have been developed over the years, especially thanks to their applied potential in quantum technologies such as quantum communication and quantum computing. Among these sources, the most commonly used in quantum optical experiments fall in two categories: heralded single photon sources and quantum dots. In the first type of source optical nonlinearities are exploited to create photon pairs, followed by the detection of one of the photons and the corresponding projection of the second one on a single photon Fock state^{22}. The advantages of these sources are that they can be very brilliant and, more importantly for the present experiment, the extraction efficiency of the photons from the source approaches unity. The main drawback of these sources is that they are probabilistic in nature, and there always exists a non-zero probability that multiple photon pairs are emitted at the same time, thus polluting the single photon state. The typical lifetime of photons generated with parametric sources can be below one picosecond.

In the case of quantum dots, the emission of a stream of single photons is granted by the Fermionic repulsion of electrons confined in quasi 0-dimensional nanostructures^{23}, often embedded in a semiconductor substrate. There are two main disadvantages of quantum dots; the first is that they generally operate at temperatures of the order of a few Kelvins, the second is that the extraction efficiency from the source is usually less than 50%. This second issue is of particular importance for the proposed experiment; indeed the majority of the photons are generally scattered inside the semiconductor containing the quantum dot, to be quickly absorbed by the substrate. This high probability of absorption before reaching the detectors could result in a change in the collapse dynamics, hindering the experiment. The typical lifetime of photons generated by quantum dots is of the order of tens to hundreds of picoseconds.

Concerning the detectors, the most performant existing single photon detectors at optical and near infrared frequencies are Superconducting Single Photon Detectors (SSPDs)^{24}. These devices consist in superconducting wires driven near to the critical current of the superconducting material. If properly designed, the energy of even a single photon absorbed by the wire is sufficient to deposit enough heat to break the superconducting state, thus generating a voltage spike. The time resolution of SSPDs is of the order of a few tens of picoseconds, and their quantum efficiencies are close to unity, generally larger than 95%. The voltage spike generated by a detection event in SSPDs is then electronically amplified giving rise to electrical pulses. For a general set-up, we can assume such pulses to be 10 ns in time width and 10 V in amplitude. If the circuit is closed on a 50 Ohm load, each pulse carries a charge of approximatively \(10^{10}\) electrons, charge that is provided by capacitive elements within the amplifier circuit (the circuit then needs time to recharge, the so called “dead time” of the detectors).

If we assume the electronic pulse following detection events to be the “pointer”, and assume that the set of observables to be sharpened is given by mass densities as in the last realisation discussed in Ref.^{3}, the value of the parameter \(\gamma \) would be *significantly* smaller than \(\gamma _2\), resulting in collapse times much longer than 1 ns. It seems therefore possible to build, with existing technologies, an experiment as that outlined in Figs. 1 or 2 in which the collapse dynamics is longer than the time resolution given by the photon lifetime and the resolution of the detectors (expected to be hundreds of ps at the most). Such an experiment remains however challenging, given in particular the requirement that the almost totality of photons must be succesfully routed to the detectors, to avoid the possibility of collapse due to absorption of the photons from the various objects constituting the experimental set-up. One promising route to minimize this problem might be the use of a fully integrated experiment, in which single photons generated by a quantum dot are not extracted from the semiconductor, but instead emitted in an optical waveguide fabricated in the semiconductor itself. This process can be engineered to have high efficiency thanks to the Purcell effect^{25}. The photons could then be routed toward monolithically integrated SSPDs. Recent experimental results^{26} again show that such a goal can be considered within reach of existing photonic technologies.

Albeit the qualitative features of collapse dynamics, as previously shown, do not depend of the value of the parameter \(\gamma \), collapse times are sensitive to the details of the particular detector employed. A tailored analysis is then required, taking into account all the particular aspects of the experimental setup adopted, and is left to future investigation.

## References

Schlosshauer, M. Decoherence, the measurement problem, and interpretations of quantum mechanics.

*Rev. Mod. Phys.***76**, 1267–1305 (2005).Ghirardi, G. C., Rimini, A. & Weber, T. Unified dynamics for microscopic and macroscopic systems.

*Phys. Rev. D***34**, 470 (1986).Ghirardi, G. C., Nicrosini, O. & Rimini, A. What really matters in Hilbert-space stochastic processes. In

*Collapse of the Wave Function: Models, Ontology, Origin, and Implications*(ed. Gao, S.) 12–22 (Cambridge University Press, 2018).Wechsler, S. In praise and in criticism of the model of continuous spontaneous localization of the wave-function. Preprint at http://arxiv.org/abs/Quantum (2020).

Ghirardi, G. C., Pearle, P. M. & Rimini, A. Markov processes in Hilbert space and continuous spontaneous localization of systems of identical particles.

*Phys. Rev. A***42**, 78–79 (1990).Bassi, A., Lochan, K., Satin, S., Singh, T. P. & Ulbricht, H. Models of wave-function collapse, underlying theories, and experimental tests.

*Rev. Mod. Phys.***85**, 471–527 (2013).Diósi, L. Continuous quantum measurement and it\(\hat{\text{ o }}\) formalism.

*Phys. Lett. A***129**(8), 419–423 (1988).Gisin, N. Quantum measurements and stochastic processes.

*Phys. Rev. Lett.***52**, 1657–1660 (1984).Adler, S. L., Brody, D. C., Brun, T. A. & Hughston, L. P. Martingale models for quantum state reduction.

*J. Phys. A Math. Gen.***34**(42), 8795–8820 (2001).Adler, S. L. Environmental influence on the measurement process in stochastic reduction models.

*J. Phys. A Math. Gen.***35**(4), 841–858 (2002).Adler, S. L. Weisskopf-Wigner decay theory for the energy-driven stochastic Schrödinger equation.

*Phys. Rev. D***67**(2), 025007 (2003).Brody, D. C. & Hughston, L. P. Efficient simulation of quantum state reduction.

*J. Math. Phys.***43**(11), 5254–5261 (2002).Diósi, L. Continuous quantum measurement and itô formalism.

*Phys. Lett. A***129**(8–9), 419–423 (1988).Gisin, N. Stochastic quantum dynamics and relativity.

*Helv. Phys. Acta***62**, 363–371 (1989).Hughston, L. P. Geometry of stochastic state reduction.

*Proc. R. Soc. Lond. A***452**, 953–979 (1996).Penrose, R. On gravity’s role in quantum state reduction.

*Gen. Relat. Gravit.***28**, 581–600 (1996).Percival, I. C. Primary state diffusion.

*Proc. R. Soc. Lond. A***447**, 189–209 (1994).Nicrosini, O. & Rimini, A. On the relationship between continuous and discontinuous stochastic processes in Hilbert space.

*Found. Phys.***20**, 1317–1327 (1990).Mello, P. & Johansen, L. Measurements in quantum mechanics and von Neumann’s model.

*AIP Conf. Proc.***1319**, 12 (2010).Adler, S. L., Bassi, A. & Ferialdi, L. Minimum measurement time: Lower bound on the frequency cutoff for collapse models.

*J. Phys. A Math. Theor.***53**(21), 215302 (2020).Piscicchia, K.

*et al.*Csl collapse model mapped with the spontaneous radiation.*Entropy***19**(7), 319 (2017).Castelletto, S. A. & Scholten, R. E. Heralded single photon sources: A route towards quantum communication technology and photon standards.

*Eur. Phys. J. Appl. Phys.***41**(3), 181–194 (2008).Yasuhiko, A. & Mark, J. H. Progress in quantum-dot single photon sources for quantum information technologies: A broad spectrum overview.

*Appl. Phys. Rev.***7**(2), 021309 (2020).Zhang, H.

*et al.*The potential and challenges of time-resolved single-photon detection based on current-carrying superconducting nanowires.*J. Phys. D Appl. Phys.***53**(1), 013001 (2019).Liu, F.

*et al.*High purcell factor generation of indistinguishable on-chip single photons.*Nat. Nanotechnol.***13**(9), 835–840 (2018).Schwartz, M.

*et al.*Fully on-chip single-photon hanbury-brown and twiss experiment on a monolithic semiconductor-superconductor platform.*Nano Lett.***18**(11), 6892–6897 (2018).

## Acknowledgements

Our colleague and friend Alberto sadly passed away before the completion of the present work; he lives in our hearts.

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O.N.: theoretical calculation & writing. A.R.: theoretical calculation & writing. D.B.: experimental discussion & writing. S.R.: numerical simulation.

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Bajoni, D., Nicrosini, O., Rimini, A. *et al.* Collapse dynamics and Hilbert-space stochastic processes.
*Sci Rep* **11**, 22179 (2021). https://doi.org/10.1038/s41598-021-00737-1

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DOI: https://doi.org/10.1038/s41598-021-00737-1

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