Table 2 Autoantibodies selected by the random forest algorithm.

From: Classification of invasive bloodstream infections and Plasmodium falciparum malaria using autoantibodies as biomarkers

Antigen UniProt12 Function Category Location
Butyrophilin subfamily 2 member A2 (BTN2A2) Q8WVV5 Type 1 membrane protein, belongs to immunoglobulin superfamily, structurally related to family of T cell regulators (B7 family) (PMID: 23000944) Immune response, signaling Extracellular
Coiled-coil domain containing 134 (CCDC134) Q9H6E4 Secretory protein, role in transcriptional regulation and MAPK signal transduction through Raf-1/MEK/ERK and JNK/SAPK pathways (PMID: 18087676) Signaling Intracellular, secreted
F-box -containing protein 5 (FBXW5) Q969U6 Substrate recognition component of E3 ubiquitin-protein ligase complex (PMID: 10,531,035, 19,232,515) Protein modification, signaling Intracellular
Glycoprotein IX (platelet) (GP9) P14770 Platelet surface glycoprotein, single-pass type I, part of receptor complex for von Willebrand factor (VWF) (PMID: 15,381,249) Hemostasis, signaling Extracellular
Interferon gamma receptor 2 (IFNGR2) P38484 Single-pass type 1 membrane protein, forms IFN-γ receptor (together with IFNGR1), signal transduction in transcription regulation (PMID: 7673114) Immune response, signaling Extracellular
Odontogenic, ameloblast associated (ODAM) A1E959 Tooth-associated epithelia protein, cancer related (PMID: 25911094) Inflammation Intracellular, secreted
8-Subunit Human Augmin Complex (HAUS8) Q9BT25 Protein complex required for mitotic spindle assembly and centrosome integrity (PMID: 19427217, 19369198) Structure, cell cycle regulation Intracellular
Transcription initiation factor TFIID subunit 6 (TAF6) P49848 Component of transcription factor IID complex (PMID: 15601843) Signaling Intracellular