Figure 4 | Scientific Reports

Figure 4

From: Cytokines mapping for tissue-specific expression, eQTLs and GWAS traits

Figure 4

Representation of cytokine gene associations in the NHGRI-EBI GWAS Catalog. Circos plots show the proportions of top-ranked EFO (Experimental Factor Ontology) classifications for cytokines associations found in the NHGRI-EBI GWAS Catalog. These classifications were categorized by: (a) disease type, (b) disease by anatomical system (for non-oncological diseases), (c) type of measurement, (d) disease. The majority of the associations were described by several classification units, illustrated by the individual colored ribbons. Several associations were found in multi-trait studies (Supplementary Table S5). In figure panel (d), ribbons indicate associations that were both uniquely mapped and were studied together within the same framework. (e) Graph with top 20 genes by the number of corresponding associations. The numbers of unique SNPs, mapped traits and PubMed papers are also indicated.

Back to article page