Example of long-range, medium-range, short-range, and local distances in a protein distance map. The distances between residue pairs 42–47, 42–52, 42–62, and 42–67 are examples of local, short, medium, and long-range distances, respectively (left). In the heatmap plot (right), the sequence separation domain for long, medium, and short-range distances, and local distances are [24+], [12, 23], [6, 11], and [0, 5], respectively. The labels in the x and y axis refer to the residue index in the corresponding protein sequence. The diagonal line shows that the residue pair i-i have a zero distance.