Table 2 Antioxidant capacity and oxidative damage markers.

From: Hydrogen-rich water reduces inflammatory responses and prevents apoptosis of peripheral blood cells in healthy adults: a randomized, double-blind, controlled trial

Measure

PW group (n = 17–18)

HW group (n = 16–20)

PW versus HW

Baseline

Week 4

Baseline

Week 4

P

BAP (µmol/L)

2,080.6 ± 236.6

2,275.0 ± 394.5

194.4 ± 315.4*

2,109.5 ± 234.5

2,407.3 ± 303.6

297.8 ± 274.2***

0.267

d-ROMs (CARR.U)

354.9 ± 70.7

349.0 ± 56.1

– 5.9 ± 28.9

391.5 ± 98.8

384.3 ± 96.4

– 7.3 ± 38.9

0.700

8-OHdG (ng/mL)

1.99 ± 1.27

1.04 ± 0.59

– 0.94 ± 1.44*

2.05 ± 0.95

0.73 ± 0.60

– 1.32 ± 1.05***

0.144

  1. All values are means ± SDs. There were no significant differences between PW and HW groups for all measures at baseline on the basis of an unpaired t test or a Mann–Whitney U test. ∆ indicates the change from baseline to week 4. Significant differences between baseline and week 4 within each group were determined with the use of a paired t test (*P < 0.05; **P < 0.01; ***P < 0.001). P values were obtained with the use of a general linear model adjusting for the value at baseline as a covariate. PW, plain water; HW, H2-rich water; BAP, biological antioxidant potential; d-ROMs, derivatives of reactive oxygen metabolites; 8-OHdG, 8-Oxo-2-deoxyguanosine.