Table 2 Clinical outcomes of the entire population.

From: Postoperative statin treatment may be associated with improved mortality in patients with myocardial injury after noncardiac surgery

 Univariate analysisMultivariate analysisIPW analysis
No statin (n = 3,778)Statin (n = 1,331)Unadjusted HR (95% CI)P value*Adjusted HR (95% CI)P value**Adjusted HR (95% CI)P value
One-year mortality501 (13.3)81 (6.1)0.44 (0.35–0.55)< 0.0010.55 (0.41–0.74)< 0.0010.61 (0.50–0.74)< 0.001
Cardiovascular155 (4.1)43 (3.2)0.75 (0.54–1.05)0.100.76 (0.49–1.18)0.220.86 (0.67–1.12)0.26
Noncardiovascular346 (9.2)38 (2.9)0.30 (0.21–0.42)< 0.0010.42 (0.28–0.63) < 0.0010.43 (0.32–0.57)< 0.001
Overall mortality945 (25.0)199 (15.0)0.60 (0.51–0.70)< 0.0010.62 (0.51–0.76) < 0.0010.70 (0.54–0.90)0.006
Cardiovascular398 (10.5)116 (8.7)0.85 (0.69–1.05)0.120.72 (0.55–0.94)0.021.35 (0.94–1.94)0.10
Noncardiovascular547 (14.5)83 (6.2)0.42 (0.33–0.53)< 0.0010.53 (0.40–0.71) < 0.0010.39 (0.26–0.58)< 0.001
  1. Data are presented as n (%) or mean (± standard deviation).
  2. *Covariates for multivariable analysis include preoperative statin treatment + age + male + diabetes + hypertension + ischemic heart disease + chronic kidney disease + heart failure + stroke + arrhythmia + surgical high risk + general anesthesia + emergency operation + operative duration + intraoperative red blood cell transfusion + intraoperative inotropic infusion + in-hospital coronary revascularization + in-hospital ventilator + in-hospital intensive care unit + antiplatelet agent + beta blocker + calcium channel blocker + renin–angiotensin–aldosterone system inhibitor.
  3. **Multivariable analysis was further conducted in IPTW analysis after retaining preoperative statin treatment + age + diabetes + hypertension + smoking + active cancer + emergency operation + in-hospital coronary revascularization + antiplatelet agent + warfarin.