Table 1 Demographics and Immunosuppression Regimens of Transplant Recipients in the Influenza Infection and Vaccine Cohorts.

From: T-cell responses following Natural Influenza Infection or Vaccination in Solid Organ Transplant Recipients

 Influenza infection (n = 31)Influenza vaccine (n = 25)p-value
Demographics
Age, y, median (IQR)54.8 (39.0–63.9)59.0 (49.5–62.5)0.239
Male sex19 (61.3)22 (88.0)0.034
Time after transplant, y, median (IQR)2.4 (0.2–4.9)3.5 (1.0–7.5)0.259
Type of transplant
Kidney13 (41.9)6 (24.0)0.001
Liver0 (0)5 (20.0)
Lung16 (51.6)5 (20.0)
Heart2 (6.5)4 (16.0)
Combined0 (0)5 (20.0)
Immunosuppression
ATG in the last 3 months4 (12.9)1 (4.0)0.367
Prednisone31 (100)19 (76.0)0.005
          daily dose (mg), median (IQR)15.0 (7.5–20.0)5.0 (1.3–5.0)<0.001
Calcineurin inhibitor31 (100)31 (100)
Tacrolimus16 (51.6)16 (64.0)0.352
          trough (µg/l), median (IQR)8.1 (5.9–12.5)6.8 (4.4–8.9)0.251
Cyclosporine15 (48.4)9 (36.0)0.352
          trough (µg/l), median (IQR)206 (163–256)145 (102–271)0.283
Sirolimus0 (0)1 (4.0)0.446
MMF19 (61.3)18 (72.0)0.4
          daily dose (mg), median (IQR)1440 (720–1440)1040 (720–1440)0.169
Azathioprine1 (3.2)3 (12.0)0.314
  1. IQR: interquartile range; ATG: antithymocyte globulin; MMF: mycophenolate mofetil.