Figure 6 | Scientific Reports

Figure 6

From: Binding of Filamentous Actin to CaMKII as Potential Regulation Mechanism of Bidirectional Synaptic Plasticity by β CaMKII in Cerebellar Purkinje Cells

Figure 6

Temporal evolution of active CaMKII and PP2B during the application of PF and CF input. Evolution of concentrations of CaMKIIac (blue) and PP2Bac (red) in wild-type mice (top, solid) and Camk2b knockout mice (bottom, dashed) in response to low calcium concentrations as a result of the PF input alone (A), pulse amplitude of 1.8 μM), and high calcium concentrations resulting from coincident PF and CF stimulation (B), pulse amplitude of 10 μM). In this figure, simulations last 300 s which is the duration of calcium stimulation.

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