Table 3 Negative and positive percentage agreement between PCR and IHC assays at clinically relevant PDL1 expression cutoff levels.

From: Agreement between PDL1 immunohistochemistry assays and polymerase chain reaction in non-small cell lung cancer: CLOVER comparison study

 SP142SP26322C3
First-lineSecond-lineFirst-lineSecond-lineFirst-lineSecond-line
PCRProbability of negative IHC assay, given negative PCR
91%97%91%91%97%70%
Probability of positive IHC assay, given positive PCR
27%9%26%26%17%45%
  1. PCR - polymerase chain reaction, IHC – immunohistochemistry.