Table 1 Comparison of available annotations for Functionally enigmatic genes vs. well-studied genes.

From: Functionally Enigmatic Genes in Cancer: Using TCGA Data to Map the Limitations of Annotations

  Functionally Enigmatic Well-studied
GO Unclassified 10.8% <0.05%
GO Slim Unclassified 53% 32%
Panther Pathways Unclassified 93% 68%
  1. Functionally enigmatic genes were more likely to be unclassified in GO, the narrower and precise annotations in GO Slim, as well as Panther Pathways. All differences were significant (p value <0.05) by a chi-square test.