Table 2 Clinical performance of the constructed OAB predictive models based on the prevalence range of OAB in female and male.

From: New participant stratification and combination of urinary biomarkers and confounders could improve diagnostic accuracy for overactive bladder

 Based on maximum Youden Index (J)Based on prevalence range of OAB in femaleBased on prevalence range of OAB in male
Lower end 9%Top end 43%Lower end 7%Top end 27%
Predictive modelPcluster 2 cut-offSensitivity (%)Specificity (%)PPV (%)NPV (%)PPV (%)NPV (%)PPV (%)NPV (%)PPV (%)NPV (%)
Combination 100.5167691896627414974485
Combination 120.4681531597577912973988
Combination 140.4674631696607613974287
Combination 150.5665762196677417975085
Combination 170.5666762196677517975086
Combination 180.5167691896627414974485
Urodynamic DOa 54681494566611953880
  1. Pcluster 2 = Probability of an individual being in the identified high OAB symptomatic score group; PPV = Positive predictive value; NPV = Negative predictive value.
  2. aSensitivity and specificity values for urodynamic test was obtained from Digesu et al.23 study where the presence of DO was used as a marker for diagnosing those presenting with OAB symptoms.