Table 1 Post-hoc tests of psilocybin effects on self-report measures of affect.

From: Emotions and brain function are altered up to one month after a single high dose of psilocybin

MeasureBaseline1 weekBaseline vs 1 week1 monthBaseline vs 1 month1 week vs
1 month
Mean (SE)Mean (SE)z, pMean (SE)z, pz, p
Joy (DPES)5.45 (0.21)6.02 (0.17)3.06, 0.0075.92 (0.21)2.92, 0.0070.08, 0.939
Content (DPES)5.62 (0.24)6.27 (0.16)2.97, 0.0096.13 (0.23)2.49, 0.0260.43, 0.667
Pride (DPES)5.42 (0.22)5.96 (0.14)2.85, 0.0095.95 (0.18)3.05, 0.0070.25, 0.805
Compassion (DPES)5.75 (0.31)6.25 (0.26)3.55, 0.0016.00 (0.30)3.18, 0.0030.26, 0.798
Amusement (DPES)5.02 (0.31)5.60 (0.32)3.11, 0.0045.71 (0.31)3.59, 0.0010.58, 0.565
Stress (DASS)4.91 (1.06)2.00 (0.60)2.95, 0.0093.27 (1.12)1.81, 0.1411.09, 0.276
Negative Affect (PANAS-X)16.09 (1.00)12.36 (0.93)4.28, 0.0000613.91 (1.03)2.50, 0.0251.68, 0.093
Tension (POMS)4.82 (1.22)1.73 (0.49)3.52, 0.00133.82 (1.19)1.23, 0.2192.21, 0.054
Depression (POMS)3.36 (0.81)0.55 (0.25)3.20, 0.0042.64 (1.03)0.87, 0.3852.29, 0.044
Total Mood Disturbance (POMS)3.64 (5.67)−10.5 (3.23)3.37, 0.002−3.55 (6.19)1.69, 0.1811.59, 0.181
State Anxiety (STAI)28.0 (2.41)22.82 (1.37)2.80, 0.01625.64 (2.56)1.31, 0.3091.42, 0.309
Trait Anxiety (STAI)31.36 (1.91)28.55 (1.32)2.11, 0.07027.55 (1.95)2.65, 0.0240.60, 0.549
  1. DASS: Depression, Anxiety, and Stress Scale; DPES: Dispositional Positive Emotion Scale; PANAS-X: Positive and Negative Affect Schedule - X; POMS: Profile of Mood States; STAI: State-Trait Anxiety Index; SE: standard error of the mean. Post-hoc tests were conducted using Tukey’s method for correcting for multiple comparisons101. Significant comparisons (α = 0.05, corrected) are indicated in bold font.