Figure 5 | Scientific Reports

Figure 5

From: Pharmacogenomics of poor drug metabolism in Greyhounds: Cytochrome P450 (CYP) 2B11 genetic variation, breed distribution, and functional characterization

Figure 5

Breed variation in CYP2B11 haplotypes in Sighthounds and other breeds. CYP2B11-H2 and -H3 genotypes were determined using 2,057 DNA samples collected from 64 different breeds, including 19 Sighthound breeds, 45 other (non-Sighthound) breeds, and 153 mixed-breed dogs. Breeds were designated by the dog’s owner. Greyhounds were divided into two breed sub-groups based on whether they were identified by their owners as dogs registered with the National Greyhound Association (NGA*) bred for racing or were dogs registered with the American Kennel Club (AKC**) bred for other purposes. Haplotype frequencies are shown for individual breeds grouped into “Sighthound dog breeds” and “Other dog breeds” for comparison. Shown next to the breed name are the number of individual dogs that were sampled. At least 10 dogs were sampled per breed.

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