Figure 5 | Scientific Reports

Figure 5

From: Allergen-induced anxiety-like behavior is associated with disruption of medial prefrontal cortex - amygdala circuit

Figure 5

Allergen exposure increases delta and theta activity in mPFC and amygdala. (A) Schematic representation of electrode implantation sites. (B) Example histology of electrodes placed in PrL and BLA. (C) Representative raw traces of simultaneous LFP recordings from the mPFC and amygdala. (D,G) Examples of mPFC and amygdala LFP traces filtered at delta and theta frequencies (<12 Hz). (E,H) Averaged power spectra of LFPs in the mPFC and amygdala. Shaded area indicates standard errors. (F,I) OVA exposure increases delta (<4 Hz) and theta (4–12 Hz) power spectral density of the mPFC and amygdala LFPs. The horizontal bars represent mean values. Data were analyzed by t-test, n = 8 per group. *p < 0.05, **p < 0.01 compared to control. OVA, ovalbumin; mPFC, medical prefrontal cortex; PrL, prelimbic; BLA, basolateral amygdala; LFP, local field potential.

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