IL-6 change as a function of training module and baseline inflammation. The effect of baseline IL-6 concentration is illustrated through model predictions of IL-6 change when setting baseline concentration to low, medium, or high. The three baseline inflammation categories correspond to cut-off values from the 25th (i.e., low baseline), 50th (i.e., medium baseline), and 75th (i.e., high baseline) percentile of the sample population. (A, B) estimated average change per module for low and medium baseline IL-6 levels, respectively. (C) estimated average change per module, and change per module and time point, for high baseline IL-6. Error bars represent +/− 1 SEM; ΔIL-6, change in ln-transformed interleukin-6; BL, baseline [inflammation]; NT, no training; Pr, Presence; Pe, Perspective; Af, Affect; °, trend at 0.05 < p < = 0.1; *significant at p < = 0.05.