Folliculogenesis occurs normally in Ikbkap mutant female mice. (A) The images of the ovaries from 4-month-old Ctrl and CKO mice were captured using a light microscope. Scale bars, 1 mm. (B) Ovary weight at 2, 4, 7, and 8-month old Ctrl and CKO mice (n = 4–7). (C) Hematoxylin and Eosin (H&E) staining of ovaries from 4-month-old females. The overall development of follicles and corpora lutea (CL) in CKO mice was found to be unaffected compared to Ctrl mice. Scale bar, 200 μm. (D) Quantification of the different types of follicles per ovarian section. At least five sections per ovary from at least three mice per genotype were analyzed. Data are presented as the mean ± SEM.