Correction to: Scientific Reports https://doi.org/10.1038/s41598-019-41110-7, published online 15 March 2019

This Article contains an error in the Figure legends of Figure 3 and Figure 4. The legends of these Figures were inadvertently switched.

The legend of Figure 3:

“Association between genotype data at rs2611513 and DNA methylation levels at GWS CpG site cg17426237. rs2611513 associated with DNA methylation levels at cg17426237; C allele associated with lower DNA methylation in (A) all sample (n = 141, p = 0.025), and (B) OD cases (n = 112; p = 0.042). No association was obtained in (C) opioid-exposed controls (n = 29; NS). *Represents p < 0.05.”

should read:

“Association between genome-wide significant (GWS) CpG sites and opioid dependence (OD)-related traits. DNA methylation (beta values) of GWS CpG sites associated with OD-related traits are shown: (AC) OD symptoms, (DF) age of onset (years), (GI) duration of opioid use (years), (JL) longest duration of chronic opioid use (years). Significant threshold is set at p < 0.05.”

The legend of Figure 4:

“Association between genome-wide significant (GWS) CpG sites and opioid dependence (OD)-related traits. DNA methylation (beta values) of GWS CpG sites associated with OD-related traits are shown: (AC) OD symptoms, (DF) age of onset (years), (GI) duration of opioid use (years), (JL) longest duration of chronic opioid use (years). Significant threshold is set at p < 0.05.”

should read:

“Association between genotype data at rs2611513 and DNA methylation levels at GWS CpG site cg17426237. rs2611513 associated with DNA methylation levels at cg17426237; C allele associated with lower DNA methylation in (A) all sample (n = 141, p = 0.025), and (B) OD cases (n = 112; p = 0.042). No association was obtained in (C) opioid-exposed controls (n = 29; NS). *Represents p < 0.05.”