Figure 2 | Scientific Reports

Figure 2

From: HIV-Negative Cryptococcal Meningoencephalitis Results in a Persistent Frontal-Subcortical Syndrome

Figure 2

Neuropsychological (NP) composite scores for cryptococcal meningoencephalitis (CM; darker grey bar) survivors compared with Pittsburgh Compound B-Positive (PIB+) mild cognitive impairment/Alzheimer’s disease (MCI/AD; lighter grey bar) patients. NP scores of a cohort of previously healthy, HIV-negative patients with cryptococcal meningoencephalitis (N = 27) were compared to a sample of PIB+ MCI/AD patients (N = 32), matched on average T-score. NP comparison with MCI/AD patients suggests relative deficits in psychomotor and executive function domains in CM patients. Significant differences between CM and MCI/AD patients were identified for memory, F(1,50) = 8.50, p = 0.005, and learning domains, F(1,50) = 11.47, p = 0.001, after controlling for mood symptoms.

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