Principal component analysis (PCA) and heat map of proteome data. (A) Principal component analysis reflecting the similarities between the heat-resistant proteome of pancreatic cancer plasma and that of plasma from healthy controls following treatment with different DNAs (eby LC/MS). The strongest similarity trend between the plasma of cancer patients and that of healthy subjects after exposure to the eDNA of P. aeruginosa are shown. (B) Heat map showing the mean spectrum counts of heat-resistant proteins in normal plasma samples following DNA treatment, and in the plasma of patients with pancreatic cancer. Black colour and yellow colours represent low and high spectral counts, respectively.