Table 3 Effect of sex on individual retinal layer thicknesses and axial length prolongation after ocular magnification adjustment.

From: Comparison of Individual Retinal Layer Thicknesses between Highly Myopic Eyes and Normal Control Eyes Using Retinal Layer Segmentation Analysis

Control Group (AL < 26 mm) Male (n = 55) Female (n = 50) Mean difference P-value*
Total retina 276.9 ± 26.8 245.6 ± 26.9 31.3 ± 5.3 <0.001
Retinal nerve fiber layer 12.6 ± 2.3 9.4 ± 2.3 3.2 ± 0.5 <0.001
Ganglion cell layer 15.2 ± 4.8 12.2 ± 5.7 3.0 ± 1.0 0.004
Inner plexiform layer 21.2 ± 4.0 17.2 ± 3.7 3.9 ± 0.8 <0.001
Inner nuclear layer 21.1 ± 6.1 16.6 ± 6.0 4.5 ± 1.2 <0.001
Outer plexiform layer 27.1 ± 7.8 24.5 ± 6.9 2.6 ± 1.5 0.075
Outer nuclear layer 90.6 ± 17.4 82.2 ± 9.5 8.4 ± 2.9 0.005
Photoreceptors 72.4 ± 5.2 69.9 ± 6.7 2.4 ± 1.1 0.036
Retinal pigment epithelium 16.6 ± 2.0 15.5 ± 3.0 1.1 ± 0.5 0.028
High Myopic Group (AL ≥ 26 mm) Male (n = 33) Female (n = 26) Mean difference P-value*
Total retina 318.4 ± 27.5 303.7 ± 19.2 14.7 ± 8.2 0.077
Retinal nerve fiber layer 14.3 ± 2.0 14.2 ± 2.6 0.1 ± 0.7 0.859
Ganglion cell layer 19.8 ± 4.8 17.5 ± 3.9 2.4 ± 1.5 0.107
Inner plexiform layer 25.3 ± 4.0 23.3 ± 3.2 1.9 ± 1.2 0.115
Inner nuclear layer 23.8 ± 4.7 23.1 ± 4.9 0.7 ± 1.5 0.616
Outer plexiform layer 34.8 ± 10.3 30.2 ± 7.6 4.6 ± 3.1 0.136
Outer nuclear layer 102.1 ± 12.0 100.9 ± 13.8 1.2 ± 3.9 0.762
Photoreceptors 80.2 ± 3.7 78.8 ± 5.0 1.4 ± 1.3 0.259
Retinal pigment epithelium 19.2 ± 2.4 16.5 ± 2.3 2.7 ± 0.8 0.001
  1. AL, axial length.
  2. Values are presented as mean thickness ± standard deviation (µm).
  3. P values were yielded by student t-test between male and female in each group divided by AL.
  4. *Bold values indicate statistically significant differences (P < 0.05).